BIOINFORMATICS SCIENTIST - NATIONAL FACILITY FOR DATA HANDLING AND ANALYSIS

APPLICATION CLOSING DATE.
April 22nd, .
About the institute Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health.
HT has the mission of conducting cutting-edge research and to translate innovation into methods and tools available to the entire National scientific community.
To this end, HT is opening National Facilities that will provide world-class research infrastructure in the areas of Structural Biology, Light Imaging Microscopy, Genomics, Genome Engineering, and Data Handling and Analysis, aimed at The National Facility for Data Handling and Analysis (NF-DaHa) will perform in-depth analysis of biological data using state-of-the-art computational methods for bioinformatics and image processing.
NFDHA comprises three Infrastructural Units (IU).
• IU1 Bioimage Analysis • IU2 Omics Analysis • IU3 Technology Development – DevOps and Web Development IU2 (Omics Analysis) performs computational analysis of large datasets generated by high-throughput DNA and RNA sequencing.
Relying on standardized and validated analysis pipelines, the unit will be responsible for the bioinformatics analysis of a variety of data types, ranging from genomic and transcriptomic data, to epigenetics, single-cell profiling and proteomics.
The team will work on data generated by other HT facilities, or by externally generated data provided by users of the facility subject to appropriate quality control.
IU2 is currently looking to expand its core team with highly motivated people who will help shape the future of scientific research in Italy, establishing high-quality standards, and delivering state-of-the-art analysis services.
We are now looking for an experienced Bioinformatics analyst who will take responsibility for analysis projects performed by the unit.
The successful candidate will be intimately familiar with the most common applications of NGS technologies for genomic analysis (RNA-Seq, ChIP-Seq, ATAC-Seq, etc) and with the appropriate analysis pipelines for each.
The candidate will be able to lead analysis projects from the initial quality control phase all the way to critical assessment of results and their delivery to the facility users, using established analysis pipelines or proposing improvements to them when necessary.
The candidate will work in close collaboration with the other members of the team (including data analysts and junior bioinformaticians) in an open environment that fosters interdisciplinary interactions and provides constant opportunities for scientific and personal growth.
Other activities include training (both internal to the group and aimed at external users), collaborations with HT research groups, and technology development.
Solid programming skills in Python and/or R, appropriate statistical/mathematical background, and knowledge of basic biology are required.
familiarity with pipeline development, experimental data quality control, container systems, HPC and Linux systems are also required.
Familiarity with pipeline development frameworks such as Nextflow, containerization technologies, HPC / Linux environments, and single-cell technologies represent strong preferential requirements.
International candidates, women and members of ethnic minorities are particularly encouraged to apply.
Key tasks and responsibilities • Lead analysis projects for internal and external facility users.
• Maintain bioinformatics analysis infrastructure.
• Closely follow developments in the field, interacting with the computational biology community at large.
• Propose, implement, and validate improvements to analysis pipelines with the collaboration of data scientists and junior bioinformaticians in the unit.
• Evaluate and criticize experiment design, critically assess intermediate and final pipeline results.
• Collaborate on the development and execution of training activities offered by the National Facility.
Essential requirements • A master’s degree in a relevant subject, e.
.
computational biology, computer science, data analysis and statistics.
• 3 or more years of documented hands-on experience in bioinformatics applied to next-generation sequencing data, and ideally in two or more of the data types listed above.
• Documented experience with setting up bioinformatics pipelines and robust standard operating procedures for quality assurance.
• Excellent computational and analytical skills, including trouble-shooting.
• Proficiency in Python and/or R.
• Fluency in English – HT is an international research institute.
Preferred requirements • Familiarity with pipeline development frameworks (e.
.
Nextflow); • Experience with the analysis of single-cell data and data generated by long-read sequencing technologies; • Experience with HPC / Linux environments, including Bash scripting and the SLURM scheduler.
Experience in the analysis of human samples; Familiarity with source code management systems (e.
.
git, gitlab), CI/CD.
Organizational and social skills • Ability to interact effectively with other team members and work synergistically to drive projects forward; • Ability to handle multiple concurrent projects with competing priorities and requirements; • Attention to detail, organization, care for quality of work; • Ability to interact effectively with the researchers involved in assigned projects, to get detailed descriptions of project goals, timelines and requirements to derive precise technical requirements and timeline estimations for projects completion; • Ability to work in a multi-cultural, multi-ethnic environment with sensitivity and respect for diversity.
Application Instructions Please apply by sending.
1.
a CV 2.
a motivation letter in English 3.
names and contacts of 2 referees (optional) For any inquiry about the call, please feel free to contact Alberto Riva (head of facility) at (this email address should not be used to send applications).
Why Human Technopole HT seeks scientific excellence.
We recruit the best scientific talents through international, open calls.
Our working environment is multicultural, friendly, and inclusive.
Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches.
We believe that highly diverse teams yield the best and most innovative results.
We engage in outward-facing scientific activities aimed at benefiting the national and international research communities.
Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.
Main benefits • Welfare plans.
• Support for relocation.
• Researchers of any nationality moving to Italy, or returning after living abroad, benefit from very attractive income tax benefits.
• Hybrid in-presence/remote work policy.
• Institutional Laptop.
• Canteen delivery service.
• Counselling.
Other details • Special consideration will be given to candidates who are part of the protected categories list, according to L.
.
• Number of positions offered.
2.
• Contract offered.
CCNL Chimico Farmaceutico – employee level, fixed term 3 years.
• The position is based in Milano, Italy.
• Salary.
up to 41K.
tax benefits where applicable.
” The Foundation reserves the right, at its sole discretion, to extend, suspend, modify, revoke, or cancel this job posting without giving rise to any rights or claims whatsoever in favor of the candidates; the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and/or obstructive circumstances”.
Tagged as.
Life Sciences