EXTRACELLULAR VESICLES DERIVED FROM PRECONDITIONED MESENCHYMAL STEM CELL: A NEW CHALLENGE FOR AD THERAPY?
Descrizione dell'offerta di lavoro
Post-doctoral Position Deadline.
1 April Employment Start Date.
1 May Contract Length.
Two-years City.
Verona Country.
Italy Institution.
University of Verona Department.
Department of Neurosciences, Biomedicine and Movement Sciences Description.
Project.
the main aim is to characterize in vivo the protective action of preconditioned Mesenchymal stem cells extracellular vesicles (MSC-EVs) relatively to amyloid precursor protein processing and amyloid β formation, microtubule associated protein tau phosphorylation and aggregation, neuroinflammation, and glial cell activation, in an animal model of Alzheimer’s disease (3xTg-AD).
The project is funded by MUR of Italy (PRIN ).
Initially the position is for one year, but it can be extended for a second year.
From selected candidate is expected to apply cell cultures, immunohistochemical and imaging techniques.
Required skills.
Experience in cellular cultures, animal handling and behavior, cellular imaging (confocal-two photon imaging), and image analysis with Image/Imaris.
Experience in biochemical and/or electrophysiology techniques is welcome, but not mandatory.
Interested candidates should send by email to Prof.
Mario Buffelli () a letter of interest and a CV.
Mario Buffelli, M.
., Ph.
.
Department of Neurosciences, Biomedicine and Movement Sciences, Section of Physiology and Psychology, University of Verona, Strada Le Grazie Verona, Italy.
Dettagli dell'offerta
- Imprecisato
- Tutta l'Italia
- Imprecisato - Imprecisato
- 08/04/2024
- 07/07/2024
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